陕西地区肝衰竭病因构成及变迁特点分析(3)-陕西教育(教学版)杂志社投稿

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陕西地区肝衰竭病因构成及变迁特点分析(3)

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综上，HBV感染仍然是我国陕西地区肝衰竭的首要病因，药物性及酒精性肝衰竭呈升高趋势，HBV感染相关肝衰竭发病年龄增加。慢性HBV感染的管理仍然是控制肝衰竭的重要环节，同时需加强酒精性及药物性肝病的防治，高龄人群肝衰竭的救治需加强重视。

[1]SHI Y, YANG Y, HU Y, et al. Acute-on-chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults[J]. Hepatology, 2015, 62(1): 232-242.

[2]BAJAJ JS, MOREAU R, KAMATH PS, et al. Acute-on-chronic liver failure: Getting ready for prime time?[J]. Hepatology, 2018, 68(4): 1621-1632.

[3]WANG YM, ZHAO XL. More attention to hotspots and difficulties in research on liver failure[J]. J Clin Hepatol, 2018, 34(9):1819-1823. (in Chinese)

王宇明, 赵学兰. 重视肝衰竭热点与难点的研究[J]. 临床肝胆病杂志, 2018, 34(9): 1819-1823.

[4]GUSTOT T, JALAN R. Acute-on-chronic liver failure in patients with alcohol-related liver disease[J]. J Hepatol, 2019, 70(2): 319-327.

[5]XU B, LIN L, XU G, et al. Long-term lamivudine treatment achieves regression of advanced liver fibrosis/cirrhosis in patients with chronic hepatitis B[J]. J Gastroenterol Hepatol, 2015, 30(2): 372-378.

[6]WU CY, LIN JT, HO HJ, et al. Association of nucleos(t)ide analogue therapy with reduced risk of hepatocellular carcinoma in patients with chronic hepatitis B: A nationwide cohort study[J]. Gastroenterology, 2014, 147(1): 143-151.

[7]Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association; Severe Liver Disease and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association. Guideline for diagnosis and treatment of liver failure (2018)[J]. J Clin Hepatol, 2019, 35(1): 38-44. (in Chinese)

中华医学会感染病学分会肝衰竭与人工肝学组, 中华医学会肝病学分会重型肝病与人工肝学组. 肝衰竭诊治指南(2018年版)[J]. 临床肝胆病杂志, 2019, 35(1): 38-44.

[8]LIM YS, KIM WR. The global impact of hepatic fibrosis and end-stage liver disease[J]. Clin Liver Dis, 2008, 12(4): 733-746.

[9]FAN JG. Epidemiology of alcoholic and nonalcoholic fatty liver disease in China[J]. J Gastroenterol Hepatol, 2013, 28(Suppl 1): 11-17.

[10]SHEN T, LIU Y, SHANG J, et al. Incidence and etiology of drug-induced liver injury in mainland China[J]. Gastroenterology, 2019, 156(8): 2230-2241.

[11]FENG RN, DU SS, WANG C, et al. Lean-non-alcoholic fatty liver disease increases risk for metabolic disorders in a normal weight Chinese population[J]. World J Gastroenterol, 2014, 20(47): -.

[12]ZHU JZ, ZHOU QY, WANG YM, et al. Prevalence of fatty liver disease and the economy in China: A systematic review[J]. World J Gastroenterol, 2015, 21(18): 5695-5706.

[13]LEI CJ, WU LP. Clinical types and biochemical indexes in patients with drug-induced liver failure[J/CD]. Chin J Liver Dis(Electr Version), 2018, 10(1): 70-73. (in Chinese)

雷创杰, 吴柳萍. 药物性肝衰竭患者的临床分型及生物化学指标的差异[J/CD]. 中国肝脏病杂志(电子版), 2018, 10(1): 70-73.

[14]YANG WB, CHEN EQ, BI HX, et al. Different models in predicting the short-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure[J]. Ann Hepatol, 2012, 11(3): 311-319.

[15]HUANG A, CHANG B, SUN Y, et al. Disease spectrum of alcoholic liver disease in Beijing 302 Hospital from 2002 to 2013: A large tertiary referral hospital experience from 7422 patients[J]. Medicine (Baltimore), 2017, 96(7): e6163.

[16]JEPSEN P, VILSTRUP H, SORENSEN HT. Alcoholic cirrhosis in Denmark- population-based incidence, prevalence, and hospitalization rates between 1988 and 2005: A descriptive cohort study[J]. BMC Gastroenterology, 2008, 8(1): 3.

[17]WHO. Global status report on alcohol and health[EB/OL]. (2018-09-21).

[18]LIANGPUNSAKUL S, HABER P, MCCAUGHAN GW. Alcoholic liver disease in Asia, Europe, and North America[J]. Gastroenterology, 2016, 150(8): 1786-1797.

[19]DEVARBHAVI H, CHOUDHURY AK, SHARMA MK, et al. Drug-induced acute-on-chronic liver failure in asian patients[J]. Am J Gastroenterol, 2019, 114(6): 929-937.

[20]HADEM J, TACKE F, BRUNS T, et al. Etiologies and outcomes of acute liver failure in Germany[J]. Clin Gastroenterol Hepatol, 2012,10(6): 664-669.

[21]ZHU Y, NIU M, CHEN J, et al. Hepatobiliary and pancreatic: Comparison between Chinese herbal medicine and Western medicine-induced liver injury of 1985 patients[J]. J Gastroenterol Hepatol, 2016, 31(8): 1476-1482.

[22]CHEN J. Drug-induced liver injury caused by Chinese herbal medicine cannot be neglected[J]. J Clin Hepatol, 2018, 34(6): 1169-1171. (in Chinese)

陈军. 不可忽视的中草药引起的药物性肝损伤[J]. 临床肝胆病杂志, 2018, 34(6): 1169-1171.

[23]MA GS, ZHU DH, HU XQ, et al. The drinking practice of people in China[J]. Acta Nutrimenta Sinica, 2005, 27(5): 362-365. (in Chinese)

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